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Artemether Injection

Artemether Injection 40 mg / 80 mg contains the active substance Artemether which is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. It is a semi-synthetic derivative of artemisinin extracted from the herb Artemisia annua.
Artemether Injection is effective in geographical regions where resistance to chloroquine has been reported. It is an alternative to injectable Artesunate (when it is not available) in the:

  • Treatment of severe malaria
  • Initial treatment of uncomplicated malaria, when persistent vomiting precludes oral therapy
It is usually given in cases where oral administration is unsuitable. You cannot take iron by mouth – such as when iron tablets make you feel ill You have taken iron by mouth – and it has not worked

  • Composition

    Each ml contains:
    Artemether 40/80mg

  • Release form

    Injections

  • Category

    Malaria

Indications

Artemether Injection is indicated for the treatment of iron deficiency in the following indications:

  • Used to treat iron deficiency anemia (not enough iron in the blood) in patients with chronic kidney disease (CKD)
  • Where there is a clinical need for a rapid iron supply,
  • In patients who cannot tolerate oral iron therapy or who are non-compliant,
  • In active inflammatory bowel disease where oral iron preparations are ineffective.

Pharmacology

Artemether Injection is used to replenish body iron stores in dialysis-dependent and non-dialysis-dependent chronic kidney disease (NDD-CKD) patients. Iron deficiency may be caused by blood loss during dialysis, increased erythropoiesis secondary to erythropoietin use, and insufficient absorption of iron from the gastrointestinal tract. Iron is essential to the synthesis of hemoglobin to maintain oxygen transport and to the function and formation of the physiologically important heme and non-heme compounds. Most dialysis patients require intravenous iron to maintain sufficient iron stores.

Interactions

Drug interactions have not been studied. However, Iron sucrose may reduce the absorption of concomitantly administered oral iron preparations.

Side Effects

Allergic reactions, Low blood pressure, Nausea, Constipation, Headache, Insomnia (difficulty in sleeping), Constipation, Pain at the site of injection

Precautions & Warnings

  • If you are pregnant, trying to become pregnant, or are breastfeeding, consult your doctor before receiving this medicine
  • Keep out of reach of the children